The Effect of Chemotherapy on the
Pulmonary Function Tests in Cancer
Patients with Healthy Lungs
Published: August 1, 2011 | DOI: https://doi.org/10.7860/JCDR/2011/.1442
avjot k. miglani, rajiv arora
Department of Physiology,
Punjab institute of medical sciences,
Jalandhar, Punjab, India.
Correspondence
Dr. Avjot K. Miglani
(Associate professor, (M.B.B.S, M.D) Physiology,
Punjab institute of medical sciences (PIMS), Jalandhar,
Punjab, India.
E-mail: avjotmiglani@yahoo.co.in; Mob.: 07837744009
Aim: The present study was aimed at determining the effect of chemotherapy on lung function tests.
Material and Methods: This study was conducted on 35 cancer patients with healthy lungs, who undertook cancer chemotherapy. The pulmonary function test parameters, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1)and the FEV1/FVC ratio was recorded by using a computerized spirometer, Medspiror (Med Systems (P) Ltd.Chandigarh).
Results: All parameters showed a significant decline in the patients after the 1st and 2nd cycles of chemotherapy, as compared to those prior to the chemotherapy.
Conclusion: The present study confirms the fact that chemotherapeutic drugs have a toxic effect on lungs.
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